Publications 2016
Gerl MJ, Bittl V, Kirchner S, Sachsenheimer T, Brunner HL, Lüchtenborg C, Özbalci C, Wiedemann H, Wegehingel S, Nickel W, Haberkant P, Schultz C, Krüger M, Brügger B. (2016)
Sphingosine-1-Phosphate Lyase Deficient Cells as a Tool to Study Protein Lipid Interactions.
PLoS One;11(4):e0153009.
Haberkant P, Stein F, Höglinger D, Gerl MJ, Brügger B, Van Veldhoven PP, Krijgsveld J, Gavin AC, Schultz C. (2016)
Bifunctional Sphingosine for Cell-Based Analysis of Protein-Sphingolipid Interactions.
ACS Chem Biol;11(1):222-30.
Huarte N, Carravilla P, Cruz A, Lorizate M, Nieto-Garai JA, Kräusslich HG, Pérez-Gil J, Requejo-Isidro J, Nieva JL. (2016)
Functional organization of the HIV lipid envelope.
Sci Rep. 6:34190.
Schur FKM, Obr M, Hagen W, Wan W, Jakobi AJ, Kirkpatrick JM, Sachse C, Kräusslich HG, Briggs JAG. (2016)
An atomic model of HIV-1 capsid-SP1 reveals structures regulating assembly and maturation.
Science 353 (6298), 506-508.
Callens N, Brügger B, Bonnafous P, Drobecq H, Gerl MJ, Krey T, Roman-Sosa G, Rümenapf T, Lambert O, Dubuisson J, Rouillé Y. (2016)
Morphology and Molecular Composition of Purified Bovine Viral Diarrhea Virus Envelope.
PLoS Pathog.12(3):e1005476.
Pavlovic, I., Thakor, D. T., Vargas, J. R., McKinlay, C. J., Hauke, S., Anstaett, P., Camuña, R. C., Bigler, L., Gasser, G., Schultz, C., Wender, P. A., Jessen, H. J. (2016)
A photocaged inositol-pyrophosphate: synthesis, cellular delivery, photochemical release, and its effect on PH-domain translocation.
Nat. Commun. 7, 10622. doi: 10.1038/ncomms10622.
Frank, J. A., Yushchenko, D. A., Hodson, D. J., Lipstein, N., Nagpal, J., Rutter, G. A., Rhee, J.-S., Gottschalk, A., Brose, N., Schultz*, C., Trauner*, D. (2016)
Optical control of protein translocation with a photoswitchable diacylglycerol.
Nat. Chem. Biol. 12, 755-762. doi:10.1038/nchembio.2141.
Kuchenov, D., Laketa, V., Stein, F., Salopiata, S., Klingmüller, U., Schultz, C. (2016)
FRET-based multi-parameter imaging platform for profiling intracellular signaling network activity.
Cell Chem. Biol. 23, 1550-1559.
Martin-Sanchez, F, Diamond, C, Zeitler, M, Gomez, AI, Baroja-Mazo, A, Bagnall, J, Spiller, D, White, M, Daniels, MJ, Mortellaro, A, Penalver, M, Paszek, P, Steringer, JP, Nickel, W, Brough, D, and Pelegrin, P (2016)
Inflammasome-dependent IL-1beta release depends upon membrane permeabilisation.
Cell Death Differ 23, 1219-1231.
Sandhoff K (2016)
Membrane lipids and sphingolipid activator proteins regulate lysosomal sphingolipid catabolism.
Biochimie, 130, 146-51.
Voelzmann A., Wulf A.L., Eckardt F., Thielisch M., Brondolin M., Pesch Y.Y., Sociale M., Bauer R., Hoch M. (2016)
Nuclear Drosophila CerS Schlank regulates lipid homeostasis via the homeodomain, independent of the lag1p motif.
FEBS Lett. 590(7):971-81.
Niehage, C., Karbanova, J., Steenblock, C., Corbeil, D., and Hoflack, B. (2016)
Cell Surface Proteome of Dental Pulp Stem Cells Identified by Label-Free Mass Spectrometry.
PloS one 11, e0159824.
Hinckelmann, M. V., Virlogeux, A., Niehage, C., Poujol, C., Choquet, D., Hoflack, B., Zala, D., and Saudou, F. (2016)
Self-propelling vesicles define glycolysis as the minimal energy machinery for neuronal transport.
Nature communications 7, 13233.
Schupp, M., Malsam, J., Ruiter, M., Scheutzow, A., Wierda, K.D., Söllner, T.H., Sørensen, J.B. (2016)
Interactions between SNAP-25 and Synaptotagmin-1 are involved in vesicle priming, clamping spontaneous and stimulating evoked neurotransmission.
J Neurosci. 36, 11865-11880.
Munch, A. S., Kedar, G. H., van Weering, J. R., Vazquez-Sanchez, S., He, E., Andre, T., Braun, T., Söllner, T.H., Verhage, M., Sørensen, J. B. (2016)
Extension of Helix 12 in Munc18-1 Induces Vesicle Priming.
J Neurosci 36, 6881-91.
Merklinger, E., Schloetel, J.G., Spitta, L., Thiele, C. and Lang, T. (2016)
No evidence for spontaneous lipid transfer at ER-PM membrane contact sites.
J. Membr. Biol. 249, 41-56.
Harak, C., Meyrath, M., Romero-Brey, I., Schenk, C., Gondeau, C., Schult, P., Esser-Nobis, K., Saeed, M., Neddermann, P., Schnitzler, P., Gotthardt, D., Perez-Del-Pulgar, S., Neumann-Haefelin, C., Thimme, R., Meuleman, P., Florian, W.R., De Francesco, R., Rice, CM., Bartenschlager, R., and Lohmann, V. (2016)
Tuning a cellular lipid kinase activity adapts HCV to replication in cell culture.
Nat. Microbiol. 2, 16247.
Zayas, M., Long, G., Madan, V., Bartenschlager, R. (2016)
Coordination of Hepatitis C Virus Assembly by Distinct Regulatory Regions in Nonstructural Protein 5A.
PLoS Pathog. 12, :e1005376.
Fogeron, M.L., Jirasko, V., Penzel, S., Paul, D., Montserret, R., Danis, C., Lacabanne, D., Badillo, A., Gouttenoire, J., Moradpour, D., Bartenschlager, R., Penin, F., Meier, B. H., and Bockmann, A. (2016)
Cell-free expression, purification, and membrane reconstitution for NMR studies of the nonstructural protein 4B from hepatitis C virus.
J. Biomol. NMR 65, 87-98.
Ostalecki, C., Wittki, S., Lee, J.H., Geist, M.M., Tibroni, N., Harrer, T., Schuler, G., Fackler, O.T. and Baur, A.S. (2016)
HIV Nef- and Notch1-dependent endocytosis of ADAM17 induces vesicular TNF secretion in chronic HIV infection.
EBioMedicine, 13:294-304.
Trautz, B., Pierini, V., Wombacher, R., Stolp, B., Chase, A.J., Pizzato, M. and Fackler, O.T. (2016)
Antagonism of the SERINC5 Particle Infectivity Restriction by HIV-1 Nef Involves Counteraction of Virion-associated Pools of the Restriction Factor.
J. Virol., 90:10915-10927.
Gaebler, A.; Penno, A., Kuerschner, L.; Thiele, C. (2016)
A highly sensitive protocol for microscopy of alkyne lipids and fluorescently tagged or immunostained proteins.
J Lipid Res 57, 1934-47.
Zimmer, S., Grebe, A., Bakke, S. S., Bode, N., Halvorsen, B., Ulas, T., Skjelland, M., De Nardo, D., Labzin, L. I., Kerksiek, A., Hempel, C., Heneka, M. T., Hawxhurst, V., Fitzgerald, M. L., Trebicka, J., Björkhem, I., Gustafsson, J.-Å., Westerterp, M., Tall, A. R., Wright, S. D., Espevik, T., Schultze, J. L., Nickenig, G., Lütjohann, D., and Latz, E. (2016)
Cyclodextrin promotes atherosclerosis regression via macrophage reprogramming.
Science Translational Medicine. 8, 333ra50–333ra50.
Bode N, Grebe A, Kerksiek A, Lütjohann D, Werner N, Nickenig G, Latz E, Zimmer S. (2016)
Ursodeoxycholic acid impairs atherogenesis and promotes plaque regression by cholesterol crystal dissolution in mice.
Biochem Biophys Res Commun. 478, 356-62.
Astro, V., Tonoli, D., Chiaretti, S., Badanai, S., Sala, K., Zerial, M., and de Curtis, I. (2016)
Liprin-α1 and ERC1 control cell edge dynamics by promoting focal adhesion turnover.
Sci Rep. 6, srep33653.
Murray, D.H., Jahnel, M., Lauer, J., Avellaneda, M.J., Brouilly, N., Cezanne, A., Morales-Navarrete, H., Perini, E.D., Ferguson, C., Lupas, A.N., Kalaidzidis, Y., Parton, R.G., Grill, S.W., and Zerial, M. (2016)
An endosomal tether undergoes an entropic collapse to bring vesicles together.
Nature 537(7618), 107-111.
Gaebler, A.; Penno, A., Kuerschner, L.; Thiele, C. (2016)
A highly sensitive protocol for microscopy of alkyne lipids and fluorescently tagged or immunostained proteins.
J Lipid Res 57, 1934-47.
