Publications 2017
Stoeck IK, Lee JY, Tabata K, Romero-Brey I, Paul D, Schult P, Lohmann V, Kaderali L, Bartenschlager R. (2017).
Hepatitis C virus replication depends on endosomal cholesterol homeostasis.
J Virol. 92(1). pii: e01196-17. doi: 10.1128/JVI.01196-17
Merklinger, E., Schloetel, J.G., Weber, P., Batoulis, H., Holz, S., Karnowski, N., Finke, J. and Lang, T. (2017).
The packing density of a supramolecular membrane protein cluster is controlled by cytoplasmic interactions.
Elife (accepted for publication).
Kleinecke S, Richert S, de Hoz L, Brügger B, Kungl T, Asadollahi E, Quintes S, Blanz J, McGonigal R, Naseri K, Sereda MW, Sachsenheimer T, Lüchtenborg C, Möbius W, Willison H, Baes M, Nave KA, Kassmann CM. (2017)
Peroxisomal dysfunctions cause lysosomal storage and axonal Kv1 channel redistribution in peripheral neuropathy.
Elife. pii: e23332.
Schonauer S, Körschen HG, Penno A, Rennhack A, Breiden B, Sandhoff K, Gutbrod K, Dörmann P, Raju DN, Haberkant P, Gerl MJ, Brügger B, Zigdon H, Vardi A, Futerman AH, Thiele C, Wachten D. (2017)
Identification of a feedback loop involving β-glucosidase 2 and its product sphingosine sheds light on the molecular mechanisms in Gaucher disease.
J Biol Chem;292(15):6177-6189.
Muecksch, F, Laketa V, Müller B, Schultz C, Kräusslich HG. (2017)
Synchronized HIV assembly by tunable PIP2 changes reveals PIP2 requirement for stable Gag anchoring.
eLife. doi: 10.7554/eLife.25287.
Höglinger, D., Nadler, A., Haberkant, P., Kirkpatrick, J., Schifferer, M., Stein, F., Hauke, S., Porter, F. D., Schultz, C. (2017)
Trifunctional lipid probes for comprehensive studies of single lipid species in living cells.
Proc. Natl. Acad. Sci. USA 114, 1566-1571.
Marat, A., Wallroth, A., Lo, W.-T., Mueller, R., Schultz, C., Haucke, V. (2017)
Phosphatidylinositol 3,4-bisphosphate represses nutrient signaling by mTORC1.
Science 356, 968-972 (2017). doi: 10.1126/science.aaf8310
Schifferer, M., Feng, S., Stein, F., Schultz, C. (2017)
Reversible Chemical Dimerization by rCD1.
Methods Enzymol. 583, 173-195.
Papadopoulos, T., Rhee, H.-J., Subramanian, D., Paraskevopoulou, F., Müller, R., Schultz, C., Brose, N., Rhee, J.-S., Betz, H. (2017)
Endosomal phosphatidylinositol-3-phosphate promotes gephyrin clustering and GABAergic neurotransmission at inhibitory postsynapses.
J. Biol. Chem. 292, 1160-1177.
Zuidscherwoude, M., Dunlock, V.-M. E., van den Bogaart, G., van Deventer, S.J., van der Schaaf, A., van Oostrum, J., Goedhart, J., In‘t Hout, J., Hämmerling, G. J., Tanaka, S., Nadler, A., Schultz, C., Wright, M. D., Adjobo-Hermans, M. J. W., van Spriel, A. B. (2017)
Tetraspanin microdomains control localized protein kinase C signaling in B cells.
Sci. Signal. 10, eaag2755.
Julia Sellin, Heike Schulze, Marie Paradis, Dominic Gosejacob, Cyrus Papan, Andrej Shevchenko, Olympia Ekaterina Psathaki, Achim Paululat, Melanie Thielisch, Konrad Sandhoff, Michael Hoch (2017)
Characterization of Drosophila Saposin-related mutants as a model for lysosomal sphingolipid storage diseases
Dis Model Mech.; 10(6): 737–750.)
Graf CGF, Schulz C, Schmälzlein M, Heinlein C, Mönnich M, Perkams L, Püttner M, Boos I, Hessefort M, Lombana Sanchez JN, Weyand M, Steegborn C, Breiden B, Ross K, Schwarzmann G, Sandhoff K, Unverzagt C (2017)
Synthetic glycoforms reveal carbohydrate-dependent bioactivity of human saposin D.
Angew. Chem. Int. Ed. 2017, 56, 5252-7.
Abdul-Hameed M., Breiden B., Schwarzmann G., Sandhoff K. (2017)
Lipids regulate the hydrolysis of mem-brane bound glucosylceramide by lysosomal β-glucocerebrosidase GBA1.
J Lipid Res, 58, 563-77.
Weber, P., Batoulis, H., Rink, K., Dahlhoff, S., Pinkwart, K., Söllner, T.H., Lang, T. (2017)
Electrostatic anchoring precedes stable membrane attachement of SNAP25/SNAP23 with the plasma membrane.
eLife doi: 10.7554/eLife.19394.
Trautz, B., Wiedemann, H., Lüchtenborg, C., Pierini, V., Kranich, J., Glass, B., Kräusslich, H.G., Brocker, T., Pizzato, M., Ruggieri, R., Brügger, B. and Fackler, O.T. (2017).
SERINC5 restricts HIV-1 infectivity without altering the lipid composition and organization of viral particles.
J. Biol. Chem., published online ahead of print Jun 28. pii: jbc.M117.797332. doi: 10.1074/jbc.M117.797332.
Bilkova, E., Pleskot, R., Rissanen, S., Sun, S., Czogalla, A., Cwiklik, L., Rog, T., Vattulainen, I., Cremer, P. S., Jungwirth, P., and Coskun, Ü.* (2017)
Calcium directly regulates rhosphatidylinositol 4,5-Bisphosphate head group conformation and recognition.
J Am Chem Soc 139, 4019-4024.
Alecu, I.; Tedeschi, A.; Behler, N.; Wunderling, K.; Lamberz, C.; Lauterbach, M.; Gaebler, A.; Ernst, D.; Van Veldhoven, P.; Al-Amoudi, A.; Latz, E.; Othman, A.; Kuerschner, L.; Hornemann, T.; Bradke, F.; Thiele, C.; Penno, A. (2017)
Localization of 1-deoxysphingolipids to mitochondria induces mitochondrial dysfunction.
J Lipid Res 58, 42-59.
Hofmann, K.; Lamberz, C.; Piotrowitz, K.; Offermann, N.; But, D.; Scheller, A.; Al-Amoudi, A.; Kuerschner, L. (2017)
Tanycytes and a differential fatty acid metabolism in the hypothalamus.
Glia 65, 231–249.
