Publications 2015


Hackmann, Y., Joedicke, L., Panneels, V. and Sinning, I. (2015)
Expression of Membrane Proteins in the Eyes of Transgenic Drosophila melanogaster. Methods in Enzymology. 556: 219-239.


Kalaidzidis, I., Miaczynska, M., Brewińska-Olchowik, M., Hupalowska, A., Ferguson, C., Parton, R.G., Kalaidzidis, Y., and Zerial, M. (2015)
APPL endosomes are not obligatory endocytic intermediates but act as stable cargo-sorting compartments.
J Cell Biol. 211, 123-44.


Zeigerer, A., Bogorad, R. L., Sharma, K., Gilleron, J., Seifert, S., Sales, S., Berndt, N., Bulik, S., Marsico, G., D'Souza, R. C., Lakshmanaperumal, N., Meganathan, K., Natarajan, K., Sachinidis, A., Dahl, A., Holzhutter, H. G., Shevchenko, A., Mann, M., Koteliansky, V., and Zerial, M. (2015)
Regulation of liver metabolism by the endosomal GTPase Rab5.
Cell reports 11, 884-892

Schur FKM, Hagen WJH, Rumlova M, Ruml T, Müller B, Kräusslich HG, Briggs JAG. (2015)
Structure of the immature HIV-1 capsid in intact virus particles at 8.8 Å resolution,
Nature 517(7535):505-8.

Höhn K, Fuchs J, Fröber A, Kirmse R, Glass B, Anders-Össwein M, Walther P, Kräusslich HG, Dietrich C. (2015)

Preservation of protein fluorescence in embedded human dendritic cells for targeted 3D light and electron microscopy.
J Microsc. 259(2):121-8.

Radestock B, Burk R, Müller B, Kräusslich HG.
Re-visiting the functional Relevance of the highly conserved Serine 40 Residue within HIV-1 p6(Gag).
Retrovirology. 11:114.

Niyonzima, N., Samstad, E. O., Aune, M. H., Ryan, L., Bakke, S. S., Rokstad, A. M., Wright, S. D., Damås, J. K., Mollnes, T. E., Latz, E., and Espevik, T. (2015)
Reconstituted High-Density Lipoprotein Attenuates Cholesterol Crystal-Induced Inflammatory Responses by Reducing Complement Activation.
The Journal of Immunology. 195, 257–264.

Fackler, O.T. (2015)
Spotlight on HIV-1 Nef: SERINC3 and SERINC5 identified as restriction factors antagonized by the pathogenesis factor.
Viruses, 7: 6730 - 6738.


Martínez-Bonet, M., Palladino, C., Briz, V., Rudolph, J.M., Fackler, O.T., Relloso, M., Muñoz-Fernandez, M.A. and Madrid, R. (2015).
A conserved GPG motif in the HIV-1 Nef core is required for principal Nef-activities.
PLoS One, 10:e0145239.

Kedar, G. H., Munch, A. S., van Weering, J. R., Malsam, J., Scheutzow, A., de Wit, H., Houy, S., Tawfik, B., Söllner, T.H., Sørensen, J.B., Verhage, M. (2015)
A post-docking role of synaptotagmin 1-C2B domain bottom residues R398/399 in mouse chromaffin cells.
J Neurosci. 35,14172-82.


Balklava, Z., Niehage, C., Currinn, H., Mellor, L., Guscott, B., Poulin, G., Hoflack, B., and Wassmer, T. (2015)
The Amyloid Precursor Protein Controls PIKfyve Function.
PloS one 10, e0130485.


Richard M., Hoch M. (2015)
Drosophila eye size is determined by Innexin 2-dependent Decapentaplegic signalling.
Dev Biol. 408(1):26-40.


MacNamara, A., Stein, F., Feng, S., Schultz, C., Saez-Rodriguez, J. (2015)
A single-cell model of PIP3 dynamics using chemical dimerization.
Bioorg. Med. Chem. 23, 2868-2876.

Höglinger, D., Haberkant, P., Aguilera-Romero, A., Riezman, H., Porter, F. D., Galione, A., Platt, F. M., Schultz, C. (2015)
Sphingosine releases calcium from lysosomes.
eLife, 10616.

Nadler, A., Yushchenko, D., Müller, R., Stein, F., Feng, S., Mulle, C., Carta, M., Schultz, C. (2015)
Exclusive photorelease of signaling lipids at the plasma membrane.
Nat. Commun. 6, 10056.doi: 10.1038/ncomms10056).

Hacke M, Björkholm P, Hellwig A, Himmels P, Ruiz de Almodóvar C, Brügger B, Wieland F, Ernst AM. (2015)
Inhibition of Ebola virus glycoprotein-mediated cytotoxicity by targeting its transmembrane domain and cholesterol.
Nat Commun. 2015 Jul 9;6:7688.


Anheuser S, Breiden B, Schwarzmann G, and Sandhoff, K (2015)
Membrane lipids regulate ganglioside GM2 catabolism and GM2 activator protein activity.
J. Lipid Res. 56, 1747-61.

Imle, A., Abraham, L., Tsopoulidis, N., Hoflack, B., Saksela, K. and Fackler, O.T. (2015)
Association with PAK2 Enables Functional Interactions of Lentiviral Nef Proteins with Exocyst.
mBio, 6: e01309-15.

Beutel, O., Roder, F., Birkholz, O., Rickert, C., Steinhoff, H.J., Grzybek, M., Coskun, Ü. and Piehler, J. (2015)
A Two-Dimensional Trap for Ultrasensitive Quantification of Transient Protein Interactions.
ACS Nano DOI: 10.1021/acsnano.5b02696.

Luisoni, S., Suomalaine M., Boucke, K., Tanner, L.B., Wenk, M.R., Guan, X. L., Grzybek, M., Coskun, Ü., Greber, U.F. (2015)
Co-option of Membrane Wounding Enables Virus Penetration into Cells
Cell Host & Microbe, 18, 75-85

Zeitler M, Steringer JP, Müller HM, Mayer MP, Nickel W. (2015)
HIV-Tat Forms Phosphoinositide Dependent Membrane Pores Implicated in Unconventional Protein Secretion.
J Biol Chem. 2015 Jul 16. pii: jbc.M115.667097. [Epub ahead of print]

Schifferer, M., Feng, S., Stein, F., Tischer, C., Schultz, C., (2015)
Reversible chemical dimerizer-induced recovery of PIP2 levels moves clathrin to the plasma membrane. Bioorg.
Med. Chem. 23, 2862-2867.

MacNamara, A., Stein, F., Feng, S., Schultz, C., Saez-Rodriguez, J. (2015)
A single-cell model of PIP3 dynamics using chemical dimerization.
Bioorg. Med. Chem. 23, 2868-2876

Inés Romero-Brey, Carola Berger, Stephanie Kallis, Androniki Kolovou, David Paul, Volker Lohmann, Ralf Bartenschlager (2015)

NS5A Domain 1 and Polyprotein Cleavage Kinetics Are Critical for Induction of Double-Membrane Vesicles Associated with Hepatitis C Virus Replication.
MBio. 6, e00759.

Dujardin M, Madan V, Montserret R, Ahuja P, Huvent I, Launay H, Leroy A, Bartenschlager R, Penin F, Lippens G, Hanoulle X. (2015)
A Proline-Tryptophan Turn in the Intrinsically Disordered Domain 2 of NS5A Protein is Essential for Hepatitis C Virus RNA Replication.
J Biol Chem. 2015 Jun 17. pii: jbc.M115.644419. [Epub ahead of print]

Paul D, Bartenschlager R, McCormick C. (2015)

The predominant species of nonstructural protein 4B in hepatitis C virus-replicating cells is not palmitoylated.
J Gen Virol. 2015 Mar 4. pii: vir.0.000111. doi: 10.1099/vir.0.000111

Podkalicka J, Biernatowska A, Majkowski M, Grzybek M, Sikorski AF (2015)
MPP1 as a Factor Regulating Phase Separation in Giant Plasma Membrane-Derived Vesicles.

Biophys J, 108, 2201-11

Sezgin, E., Grzybek, G., Gutmann, T., Buhl, T., Dirkx, R., Coskun, Ü., Solimena, M., Simons, K., Levental, I., Schwille, P. (2015)

Adaptive lipid packing and bioactivity in membrane domains.
PLOS ONE, DOI: 10.1371/journal.pone.0123930

Kaszuba, K., Grzybek, M., Orlowski, A., Danne, R., Rog, T., Simons, K., Coskun, Ü. and Vattulainen I. (2015)
N-Glycosylation as determinant of Epidermal Growth Factor Receptor conformation in membranes.

PROC. NAT. ACAD. SCI. USA, 112, 4334-4339

Lenoir, M., Grzybek, M., Majkowski, M., Rajesh, S., Kaur, J., Whittaker, S.M., Coskun, Ü. and Overduin M. (2015)
Structural basis of dynamic membrane recognition by trans-Golgi network specific FAPP proteins.

JMB, 427, 966–981.

Müller HM, Steringer JP, Wegehingel S, Bleicken S, Münster M, Dimou E, Unger S, Weidmann G, Andreas H, García-Sáez AJ, Wild K, Sinning I, Nickel W. (2015)
Formation of disulfide bridges drives oligomerization, membrane pore formation, and translocation of fibroblast growth factor 2 to cell surfaces.
J Biol Chem. 2015 Apr 3;290(14):8925-37. doi: 10.1074/jbc.M114.622456. Epub 2015 Feb 18.

Responsible: Editor
Latest Revision: 2017-08-11