Publications 2015
Hackmann, Y., Joedicke, L., Panneels, V. and Sinning, I. (2015)
Expression of Membrane Proteins in the Eyes of Transgenic Drosophila melanogaster. Methods in Enzymology. 556: 219-239.
Kalaidzidis, I., Miaczynska, M., Brewińska-Olchowik, M., Hupalowska, A., Ferguson, C., Parton, R.G., Kalaidzidis, Y., and Zerial, M. (2015)
APPL endosomes are not obligatory endocytic intermediates but act as stable cargo-sorting compartments.
J Cell Biol. 211, 123-44.
Zeigerer, A., Bogorad, R. L., Sharma, K., Gilleron, J., Seifert, S., Sales, S., Berndt, N., Bulik, S., Marsico, G., D'Souza, R. C., Lakshmanaperumal, N., Meganathan, K., Natarajan, K., Sachinidis, A., Dahl, A., Holzhutter, H. G., Shevchenko, A., Mann, M., Koteliansky, V., and Zerial, M. (2015)
Regulation of liver metabolism by the endosomal GTPase Rab5.
Cell reports 11, 884-892
Schur FKM, Hagen WJH, Rumlova M, Ruml T, Müller B, Kräusslich HG, Briggs JAG. (2015)
Structure of the immature HIV-1 capsid in intact virus particles at 8.8 Å resolution,
Nature 517(7535):505-8.
Höhn K, Fuchs J, Fröber A, Kirmse R, Glass B, Anders-Össwein M, Walther P, Kräusslich HG, Dietrich C. (2015)
Preservation of protein fluorescence in embedded human dendritic cells for targeted 3D light and electron microscopy.
J Microsc. 259(2):121-8.
Radestock B, Burk R, Müller B, Kräusslich HG. (2015)
Re-visiting the functional Relevance of the highly conserved Serine 40 Residue within HIV-1 p6(Gag).
Retrovirology. 11:114.
Niyonzima, N., Samstad, E. O., Aune, M. H., Ryan, L., Bakke, S. S., Rokstad, A. M., Wright, S. D., Damås, J. K., Mollnes, T. E., Latz, E., and Espevik, T. (2015)
Reconstituted High-Density Lipoprotein Attenuates Cholesterol Crystal-Induced Inflammatory Responses by Reducing Complement Activation.
The Journal of Immunology. 195, 257–264.
Fackler, O.T. (2015)
Spotlight on HIV-1 Nef: SERINC3 and SERINC5 identified as restriction factors antagonized by the pathogenesis factor.
Viruses, 7: 6730 - 6738.
Martínez-Bonet, M., Palladino, C., Briz, V., Rudolph, J.M., Fackler, O.T., Relloso, M., Muñoz-Fernandez, M.A. and Madrid, R. (2015).
A conserved GPG motif in the HIV-1 Nef core is required for principal Nef-activities.
PLoS One, 10:e0145239.
Kedar, G. H., Munch, A. S., van Weering, J. R., Malsam, J., Scheutzow, A., de Wit, H., Houy, S., Tawfik, B., Söllner, T.H., Sørensen, J.B., Verhage, M. (2015)
A post-docking role of synaptotagmin 1-C2B domain bottom residues R398/399 in mouse chromaffin cells.
J Neurosci. 35,14172-82.
Balklava, Z., Niehage, C., Currinn, H., Mellor, L., Guscott, B., Poulin, G., Hoflack, B., and Wassmer, T. (2015)
The Amyloid Precursor Protein Controls PIKfyve Function.
PloS one 10, e0130485.
Richard M., Hoch M. (2015)
Drosophila eye size is determined by Innexin 2-dependent Decapentaplegic signalling.
Dev Biol. 408(1):26-40.
MacNamara, A., Stein, F., Feng, S., Schultz, C., Saez-Rodriguez, J. (2015)
A single-cell model of PIP3 dynamics using chemical dimerization.
Bioorg. Med. Chem. 23, 2868-2876.
Höglinger, D., Haberkant, P., Aguilera-Romero, A., Riezman, H., Porter, F. D., Galione, A., Platt, F. M., Schultz, C. (2015)
Sphingosine releases calcium from lysosomes.
eLife, 10616. http://dx.doi.org/10.7554/eLife.10616.
Nadler, A., Yushchenko, D., Müller, R., Stein, F., Feng, S., Mulle, C., Carta, M., Schultz, C. (2015)
Exclusive photorelease of signaling lipids at the plasma membrane.
Nat. Commun. 6, 10056.doi: 10.1038/ncomms10056).
Hacke M, Björkholm P, Hellwig A, Himmels P, Ruiz de Almodóvar C, Brügger B, Wieland F, Ernst AM. (2015)
Inhibition of Ebola virus glycoprotein-mediated cytotoxicity by targeting its transmembrane domain and cholesterol.
Nat Commun. 2015 Jul 9;6:7688.
Anheuser S, Breiden B, Schwarzmann G, and Sandhoff, K (2015)
Membrane lipids regulate ganglioside GM2 catabolism and GM2 activator protein activity.
J. Lipid Res. 56, 1747-61.
Imle, A., Abraham, L., Tsopoulidis, N., Hoflack, B., Saksela, K. and Fackler, O.T. (2015)
Association with PAK2 Enables Functional Interactions of Lentiviral Nef Proteins with Exocyst.
mBio, 6: e01309-15
Beutel, O., Roder, F., Birkholz, O., Rickert, C., Steinhoff, H.J., Grzybek, M., Coskun, Ü. and Piehler, J. (2015)
A Two-Dimensional Trap for Ultrasensitive Quantification of Transient Protein Interactions.
ACS Nano DOI: 10.1021/acsnano.5b02696.
Luisoni, S., Suomalaine M., Boucke, K., Tanner, L.B., Wenk, M.R., Guan, X. L., Grzybek, M., Coskun, Ü., Greber, U.F. (2015)
Co-option of Membrane Wounding Enables Virus Penetration into Cells
Cell Host & Microbe, 18, 75-85.
Zeitler M, Steringer JP, Müller HM, Mayer MP, Nickel W. (2015)
HIV-Tat Forms Phosphoinositide Dependent Membrane Pores Implicated in Unconventional Protein Secretion.
J Biol Chem. 2015 Jul 16. pii: jbc.M115.667097. [Epub ahead of print]
PMID:26183781.
Schifferer, M., Feng, S., Stein, F., Tischer, C., Schultz, C., (2015)
Reversible chemical dimerizer-induced recovery of PIP2 levels moves clathrin to the plasma membrane. Bioorg.
Med. Chem. 23, 2862-2867.
MacNamara, A., Stein, F., Feng, S., Schultz, C., Saez-Rodriguez, J. (2015)
A single-cell model of PIP3 dynamics using chemical dimerization.
Bioorg. Med. Chem. 23, 2868-2876
Inés Romero-Brey, Carola Berger, Stephanie Kallis, Androniki Kolovou, David Paul, Volker Lohmann, Ralf Bartenschlager (2015)
NS5A Domain 1 and Polyprotein Cleavage Kinetics Are Critical for Induction of Double-Membrane Vesicles Associated with Hepatitis C Virus Replication.
MBio. 6, e00759.
Dujardin M, Madan V, Montserret R, Ahuja P, Huvent I, Launay H, Leroy A, Bartenschlager R, Penin F, Lippens G, Hanoulle X. (2015)
A Proline-Tryptophan Turn in the Intrinsically Disordered Domain 2 of NS5A Protein is Essential for Hepatitis C Virus RNA Replication.
J Biol Chem. 2015 Jun 17. pii: jbc.M115.644419. [Epub ahead of print]
Paul D, Bartenschlager R, McCormick C. (2015)
The predominant species of nonstructural protein 4B in hepatitis C virus-replicating cells is not palmitoylated.
J Gen Virol. 2015 Mar 4. pii: vir.0.000111. doi: 10.1099/vir.0.000111
Podkalicka J, Biernatowska A, Majkowski M, Grzybek M, Sikorski AF (2015)
MPP1 as a Factor Regulating Phase Separation in Giant Plasma Membrane-Derived Vesicles.
Biophys J, 108, 2201-11
Sezgin, E., Grzybek, G., Gutmann, T., Buhl, T., Dirkx, R., Coskun, Ü., Solimena, M., Simons, K., Levental, I., Schwille, P. (2015)
Adaptive lipid packing and bioactivity in membrane domains.
PLOS ONE, DOI: 10.1371/journal.pone.0123930
Kaszuba, K., Grzybek, M., Orlowski, A., Danne, R., Rog, T., Simons, K., Coskun, Ü. and Vattulainen I. (2015)
N-Glycosylation as determinant of Epidermal Growth Factor Receptor conformation in membranes.
PROC. NAT. ACAD. SCI. USA, 112, 4334-4339
Lenoir, M., Grzybek, M., Majkowski, M., Rajesh, S., Kaur, J., Whittaker, S.M., Coskun, Ü. and Overduin M. (2015)
Structural basis of dynamic membrane recognition by trans-Golgi network specific FAPP proteins.
JMB, 427, 966–981.
Müller HM, Steringer JP, Wegehingel S, Bleicken S, Münster M, Dimou E, Unger S, Weidmann G, Andreas H, García-Sáez AJ, Wild K, Sinning I, Nickel W. (2015)
Formation of disulfide bridges drives oligomerization, membrane pore formation, and translocation of fibroblast growth factor 2 to cell surfaces.
J Biol Chem. 2015 Apr 3;290(14):8925-37. doi: 10.1074/jbc.M114.622456. Epub 2015 Feb 18.
