Publications 2014
Lee, J.Y., Acosta, E.G., Stoeck, I. K., Long, G., Hiet, M.S., Mueller, B., Fackler, O.T., Kallis, S. and Bartenschlager, R. (2014)
Apolipoprotein E contributes to a maturation step of infectious virus particle assembly and interacts with envelope glycoproteins.
J. Virol. 88: 12422-12437.
Traikov, S., Stange, C., Wassmer, T., Paul-Gilloteaux, P., Salamero, J., Raposo, G., and Hoflack, B. (2014)
Septin6 and Septin7 GTP binding proteins regulate AP-3- and ESCRT-dependent multivesicular body biogenesis.
PloS one 9, e109372.
Izquierdo-Useros N, Lorizate M, McLaren PJ, Telenti A, Kräusslich HG, Martinez-Picado J. (2014)
HIV-1 capture and transmission by dendritic cells: the role of viral glycolipids and the cellular receptor Siglec-1.
PLoS Pathog. 10: e1004146.
Stauffer S, Rahman SA, de Marco A, Carlson LA, Glass B, Oberwinkler H, Herold N, Briggs JA, Müller B, Grünewald K, Kräusslich HG. (2014)
The nucleocapsid domain of Gag is dispensable for actin incorporation into HIV-1 and for association of viral budding sites with cortical F-actin
J Virol. 88:7893-903.
Oninla VO, Breiden B, Babalola JO, Sandhoff K (2014)
Acid sphingomyelinase activity is regulated by membrane lipids and facilitates cholesterol transfer by NPC2.
J Lipid Res, 55, 2606-19.
Schwarzmann G, Arenz C, Sandhoff K (2014)
Labeled chemical biology tools for investigating sphingolipid metabolism, trafficking and interaction with lipids and proteins.
Biochim Biophys Acta, 1841, 1161-73.
Schulze H, Sandhoff K (2014)
Sphingolipids and lysosomal pathologies.
Biochim Biophys Acta, 1841, 799-810.
Zacherl S, La Venuta G, Müller HM, Wegehingel S, Dimou E, Sehr P, Lewis JD, Erfle H, Pepperkok R, Nickel W (2014)
A direct role for ATP1A1 in unconventional secretion of fibroblast growth factor 2.
J. Biol. Chem. 290:3654-3665.
Samstad, E. O., Niyonzima, N., Nymo, S., Aune, M. H., Ryan, L., Bakke, S. S., Lappegård, K. T., Brekke, O.-L., Lambris, J. D., Damås, J. K., Latz, E., Mollnes, T. E., and Espevik, T. (2014)
Cholesterol crystals induce complement-dependent inflammasome activation and cytokine release.
The Journal of Immunology. 192, 2837–2845.
Laketa, V. Zarbakhsh, S., Traynor-Kaplan, A., MacNamara, A., Subramanian, D., Putyrski, M., Mueller, R., Nadler, A., Mentel, M., Saez-Rodriguez, J., Pepperkok, R., Schultz, C. (2014)
PIP3 induces the recycling of receptor tyrosine kinase.
Sci. Signal. 7, ra5.
Steringer JP, Müller HM, Nickel W. (2014)
Unconventional secretion of fibroblast growth factor 2--a novel type of protein translocation across membranes?
J Mol Biol. 2015 Mar 27;427(6 Pt A):1202-10. doi: 10.1016/j.jmb.2014.07.012. Epub 2014 Jul 19. Review.
Geist MM, Pan X, Bender S, Bartenschlager R, Nickel W, Fackler OT. (2014)
Heterologous Src homology 4 domains support membrane anchoring and biological activity of HIV-1 Nef.
J Biol Chem. 2014 May 16;289(20):14030-44. doi: 10.1074/jbc.M114.563528. Epub 2014 Apr 4.
Perini ED, Schaefer R, Stöter M, Kalaidzidis Y, Zerial M. (2014)
Mammalian CORVET is required for fusion and conversion of distinct early endosome subpopulations.
Traffic. 2014 Dec;15(12):1366-89. doi: 10.1111/tra.12232. Epub 2014 Nov 6.
Czogalla, A., Kauer, D.J., Seidel, R., Schwille, P., Petrov, E.P. (2014)
DNA Origami Nanoneedles on Freestanding Lipid Membranes as a Tool To Observe Isotropic–Nematic Transition in Two Dimensions.
Nano Letters, 1, 649-55
Chatel-Chaix L, Bartenschlager R. (2014)
Dengue virus- and hepatitis C virus-induced replication and assembly compartments: the enemy inside--caught in the web.
J Virol 88(11):5907-11. doi: 10.1128/JVI.03404-13. Review
Lee JY, Acosta EG, Stoeck IK, Long G, Hiet MS, Mueller B, Fackler OT, Kallis S, Bartenschlager R. (2014)
Apolipoprotein e likely contributes to a maturation step of infectious hepatitis C virus particles and interacts with viral envelope glycoproteins.
J Virol. 88(21):12422-37.doi: 10.1128/JVI.01660-14.
Eberle CA, Zayas M, Stukalov A, Pichlmair A, Alvisi G, Müller AC, Bennett KL, Bartenschlager R, Superti-Furga G. (2014)
The lysine methyltransferase SMYD3 interacts with hepatitis C virus NS5A and is a negative regulator of viral particle production.
Virology. 462-463:34-41.
Björkholm P, Ernst AM, Hacke M, Wieland F, Brügger B*, von Heijne G. (2014)
Identification of novel sphingolipid-binding motifs in mammalian membrane proteins.
Biochim Biophys Acta. 1838(8):2066-70. *co-corresponding author.
Aim24 and MICOS modulate respiratory function, tafazzin-related cardiolipin modification and mitochondrial architecture.
Elife. 3:e01684.
Breiden B, Sandhoff K (2014)
The role of sphingolipid metabolism in cutaneous permeability barrier formation.
Biochim Biophys Acta 1841, 441-452.
Rutkowska, A., Plass, T., Hoffmann, J.-E., Yushchenko, D., Feng, S., Schultz, C. (2014)
Click meets FlAsH: a heterologous chemical cross-linker.
ChemBioChem, 15, 1765-1768.
Pelka K, Phulphagar K, Zimmermann J, Stahl R, Schmid-Burgk JL, Schmidt T, Spille JH, Labzin LI, Agrawal S, Kandimalla ER, Casanova JL, Hornung V, Marshak-Rothstein A, Höning S, Latz E. (2014)
Cutting Edge: The UNC93B1 Tyrosine-Based Motif Regulates Trafficking and TLR Responses via Separate Mechanisms.
J Immunol. 2014 Oct 1;193(7):3257-61. doi: 10.4049/jimmunol.1301886. Epub 2014 Sep 3.
Haller C, Müller B, Fritz JV, Lamas-Murua M, Stolp B, Pujol F, Keppler OT, Fackler OT. (2014)
HIV-1 Nef and Vpu are Functionally Redundant Broad-Spectrum Modulators of Cell Surface Receptors Including Tetraspanins.
J Virol. 2014 Oct 1. pii: JVI.02333-14. [Epub ahead of print]
Hoeglinger, D., Nadler, A., Schultz, C. (2014)
General Subjects, Caged lipids as tools for investigating cellular signaling.
Biochim Biophys Acta – 1841, 1085-1096.
Feng, S., Laketa, L., Stein, F., Rutkowska, A., MacNamara, A., Depner, S., Klingmueller, U., Saez-Rodriguez, J., Schultz, C. (2014)
A rapidly reversible chemical dimerizer system to study lipid signalling in living cells.
Angew. Chem. Int. Ed. 53, 6720–6723.
Grzybek M., Gutmann T., Coskun Ü. (2014)
Cell Membrane Nanodomains from Biochemistry to Nanoscopy: Functional role of membrane lipids in EGF receptor dynamics and regulation.
(Eds. Lidke, D. & Cambi A) CRC Press, Taylor & Francis Group, in press.
Czogalla A., Grzybek M., Jones W., Coskun Ü. (2014)
Validity and applicability of membrane model systems for studying interactions of peripheral membrane proteins with lipids.
BBA Molecular and Cell Biology of Lipids, 1841, pages 1049-1059.
Gerl, M.J., Sachsenheimer, T., Grzybek, M., Coskun Ü., Wieland, F.T., Brügger, B. (2014)
Analysis of Transmembrane Domains and Lipid modified Peptides with MALDI-TOF.
Analytical Chemistry, 86, 3722-3726.
Kuerschner L, Thiele C. (2014)
Multiple bonds for the lipid interest.
Biochim Biophys Acta. 2014 Aug; 1841 (8):1031-7.
Berger C, Romero-Brey I, Radujkovic D, Terreux R, Zayas M, Paul D, Harak C, Hoppe S, Gao M, Penin F, Lohmann V, Bartenschlager R. (2014)
Daclatasvir-Like Inhibitors of NS5A Block Early Biogenesis of Hepatitis C Virus-Induced Membranous Replication Factories, Independent of RNA Replication.
Gastroenterology. 2014 Jul 18. pii. S0016-5085(14)00915-9. doi: 10.1053/j.gastro.2014.07.019.
[Epub ahead of print].
Madan V, Paul D, Lohmann V, Bartenschlager R. (2014)
Inhibition of HCV replication by cyclophilin antagonists is linked to replication fitness and occurs by inhibition of membranous web formation.
Gastroenterology. 2014 May;146(5):1361-72.e1-9. doi: 10.1053/j.gastro.2014.01.055. Epub 2014 Jan 31.
Bharat TA, Malsam J, Hagen WJ, Scheutzow A, Söllner TH, Briggs JA (2014)
SNARE and regulatory proteins induce local membrane protrusions to prime docked vesicles for fast calcium-triggered fusion.
EMBO Rep. 2014 Mar;15(3):308-14. doi: 10.1002/embr.201337807. Epub 2014 Feb 3.
Geist MM, Pan X, Bender S, Bartenschlager R, Nickel W, Fackler OT. (2014)
Heterologous Src homology 4 domains support membrane anchoring and biological actitivity of HIV-1 Nef.
J Biol Chem. 2014 May 16;289(20):14030-44. doi: 10.1074/jbc.M114.563528. [Epub 2014 Apr 4].
Hofmann K, Thiele C, Schött HF, Gaebler A, Schoene M, Kiver Y, Friedrichs S, Lütjohann D, Kuerschner L. (2014)
A novel alkyne cholesterol to trace cellular cholesterol metabolism and localization.
J Lipid Res. 2014 Mar;55(3):583-91.
Parisotto D.,Pfau M., Scheutzow A., Wild K., Mayer MP., Malsam J., Sinning I., Söllner TH. (2014)
An extended helical conformation in domain 3a of the SM protein Munc18-1 provides a template for SNARE (soluble N-ethylmaleimide sensitive factor attachment protein receptor) complex assembly.
J Biol Chem. 2014 April 4;289(14)9639-50. doi: 10.1074/jbc.M113.514273. Epub 2014 Feb 14.
Niehage C., Stange C., Anitei M. and Hoflack B. (2014)
Liposome-based assays to study membrane-associated protein networks. Methods in Enzymology, 534:223-43. doi: 10.1016/B978-0-12-397926-1.00013-5.
