Publications 2011


Kaiser HJ, Surma MA, Mayer F, Levental I, Grzybek M, Klemm RW, Da Cruz S, Meisinger C, Müller V, Simons K, Lingwood D (2011)

Molecular convergence of bacterial and eukaryotic surface order
J Biol Chem. 2011 Nov 25;286(47):40631-7. Epub 2011 Sep 30.

Moessinger C, Kuerschner L, Spandl J, Shevchenko A, Thiele C (2011)

Human lysophosphatidylcholine acyltransferases 1 and 2 are located in lipid droplets where they catalyze the formation of phosphatidylcholine.

J Biol Chem. 2011 Jun 17;286(24):21330-9.

David Paul, Inés Romero-Brey, Jérôme Gouttenoire, Savina Stoitsova, Jacomine Krijnse-Locker, Darius Moradpour and Ralf Bartenschlager (2011)

NS4B Self-Interaction through Conserved C-Terminal Elements Is Required for the Establishment of Functional Hepatitis C Virus Replication Complexes
Journal of Virology, Vol. 85, No. 14, p. 6963–6976

Schollmeier, Y., Krause, J. M., Kreye, S., Malsam, J., Söllner, Th. H. (2011)

Resolving the Function of Distinct Munc18-1/SNARE Protein Interaction Modes in a Reconstituted Membrane Fusion.

JBC 286 No. 35, 30582-30590.

Pan, X., Rudolph, J.M., Abraham, L., Habermann, A., Haller, C., Krijnse-Locker, J. and Fackler, O.T. (2011)

HIV-1 Nef Compensates Disorganization of the Immunological Synapse by Assembly of an Intracellular Lck Signalosome.
Blood; 119: 786-797, published ahead of print November 28, 2011, doi:10.1182/blood-2011-08-373209.

Bauer, N., M. Wilsch-Bräuninger, J. Karbanová, A.-V. Fonseca, D. Strauss, D. Freund, C. Thiele, W.B. Huttner, M. Bornhäuser and D. Corbeil (2011)

Hematopoietic stem cell differentiation promotes the release of prominin-1/CD133–containing membrane vesicles – A role of the endocytic-exocytic pathway.

EMBO Mol. Med. 2011 Jul;3(7):398-409. doi: 10.1002/emmm.201100147. Epub 2011 May 18

Fonseca, A.-V. and D. Corbeil (2011)

The hematopoietic stem cell polarization and migration: A dynamic link between RhoA signaling pathway, microtubule network and ganglioside-based membrane microdomains.

Commun. Integr. Biol. 4: 201-204

Jászai, J., C.A. Fargeas, S. Graunper, E.M. Tanaka, M. Brand, W.B. Huttner and D. Corbeil (2011)
Distinct and conserved prominin-1/CD133-positive retinal cell populations identified across species.

PloS One. 6: e17590


Missol-Kolka, E., J. Karbanová, P. Janich, M. Haase, C.A. Fargeas, W.B. Huttner and D. Corbeil (2011)

Prominin-1 (CD133) is not restricted to stem cells located in the basal compartment of murine and human prostate.

The Prostate. 71: 254-263


Sampaio JL, Gerl MJ, Klose C, Ejsing CS, Beug H, Simons K, Shevchenko A (2011)

Membrane lipidome of an epithelial cell line.

Proc Natl Acad Sci 108(5): 1903-1907. 


Lingwood D, Binnington B, Róg T, Vattulainen I, Grzybek M, Coskun U, Lingwood CA, Simons K (2011)

Cholesterol modulates glycolipid conformation and receptoractivity.

Nat Chem Biol. (5): 260-2.


Simons K, Sampaio JL (2011)

Membrane Organization and Lipid Rafts.

Cold Spring Harb Perspect Biol. 2011 May 31.


Plass T., Schultz C. (2011)

Covalent Labeling of Biomolecules in Living Cells.

Advanced Fluorescence Reporters in Chemistry and Biology III (Ed. A. Demchenko) Springer Verlag, pp225-261


Lemke E. A., Schulz C. (2011)

Principles for designing fluorescent sensors and reporters

Nat. Chem. Biol. 7, 480-483


Mentel M. V., Laketa V., Subramanian D., Gillandt H., Schultz C. (2011)

Photoactivatable and cell membrane-permeant phosphatidylinositol 3,4,5-trisphosphate.

Angew. Chem. Int. Ed. 50, 3811-3814


Plass T., Köhler C., Schultz C., Lemke E. (2011)

Genetically encoded Copper free click chemistry.
Angew. Chem. Int. Ed. 50, 3878-3881


Schmidt A, Oberle N, Weiß EM, Vobis D, Frischbutter S, Baumgrass R, Falk CS, Haag M, Brügger B, Lin H, Mayr GW, Reichardt P, Gunzer M, Suri-Payer E, Krammer PH. (2011)

Human Regulatory T Cells Rapidly Suppress T Cell Receptor-Induced Ca2+, NF-κB, and NFAT Signaling in Conventional T Cells.
Sci Signal. 2011 Dec 20;4(204):ra90.


Sancar, G., C. Sancar, B. Brügger, N. Ha, T. Sachsenheimer, E. Gin, S. Wdowik, I. Lohmann, F. Wieland, T. Hoefer, A.C. Diernfellner, and M. Brunner (2011)
A global circadian repressor controls anti-phasic expression of metabolic genes in Neurospora.
Mol Cell 2011 Dec 9;44(5):687-97.

Yurlova L, Kahya N, Aggarwal S, Kaiser HJ, Chiantia S, Bakhti M, Pewzner-Jung Y, Ben-David O, Futerman AH, Brügger B, Simons M. (2011)

Self-segregation of myelin membrane lipids in model membranes.

Biophys J.  2011 Dec 7;101(11):2713-20.

Contreras FX, Ernst AM, Wieland F, Brügger B. (2011)

Specificity of intramembrane protein-lipid interactions.

Cold Spring Harb Perspect Biol. 2011 Jun 1;3(6). pii: a004705. Review


Ritzerfeld J, Remmele S, Wang T, Temmerman K, Brügger B, Wegehingel S, Tournaviti S, Strating JR, Wieland FT, Neumann B, Ellenberg J, Lawerenz C, Hesser J, Erfle H, Pepperkok R, Nickel W. (2011)

Phenotypic profiling of the human genome reveals gene products involved in plasma membrane targeting of SRC kinases.

Genome Res. 2011 Nov;21(11):1955-68.


Ben-David O, Pewzner-Jung Y, Brenner O, Laviad EL, Kogot-Levin A, Weissberg I, Biton IE, Pienik R, Wang E, Kelly S, Alroy J, Raas-Rothschild A, Friedman A, Brügger B, Merrill AH Jr, Futerman AH. (2011)

Encephalopathy caused by ablation of very long acyl chain ceramide synthesis may be largely due to reduced galactosylceramide levels.

J Biol Chem. 2011 Aug 26;286(34):30022-33.


Kou J, Kovacs GG, Höftberger R, Kulik W, Brodde A, Forss-Petter S, Hönigschnabl S, Gleiss A, Brügger B, Wanders R, Just W, Budka H, Jungwirth S, Fischer P, Berger J. (2011)

Peroxisomal alterations in Alzheimer's disease.

Acta Neuropathol. 2011 Sep;122(3):271-83.

Welti S, Kühn S, D'Angelo I, Brügger B, Kaufmann D, Scheffzek K. (2011)

Structural and biochemical consequences of NF1 associated nontruncating mutations in the Sec14-PH module of neurofibromin.

Hum Mutat. 2011 Feb;32(2):191-7.

Merz A, Long G, Hiet MS, Brügger B, Chlanda P, Andre P, Wieland F, Krijnse-Locker J, Bartenschlager R (2011)
Biochemical and morphological properties of hepatitis C virus particles and determination of their lipidome.
J Biol Chem. 2011 Jan 28;286(4):3018-32

Fargeas CA, Karbanová J, Jászai J and Corbeil D (2011)
CD133 and membrane microdomains: old facets for future hypotheses.
World J Gastroenterol. 2011;17(36):4149-52.

Levental I, Grzybek M, Simons K (2011)
Raft domains of variable properties and compositions in plasma membrane vesicles.
Proc Natl Acad Sci U S A. 2011 Jul 12;108(28):11411-6. Epub 2011 Jun 27.

Coskun U, Simons K (2011)
Cell membranes: the lipid perspective
Structure. 2011 Nov 9;19(11):1543-8.

Surma MA, Klose C, Klemm RW, Ejsing CS, Simons K (2011)
Generic sorting of raft lipids into secretory vesicles in yeast
Traffic. 2011 Sep;12(9):1139-47. doi: 10.1111/j.1600-0854.2011.01221.x. Epub 2011 Jun 15.

Coskun U, Grzybek M, Drechsel D, Simons K (2011)
Regulation of human EGF receptor by lipids.
Proc Natl Acad Sci U S A. 2011 May 31;108(22):9044-8. Epub 2011 May 13

Schulze H and Sandhoff K. (2011)
Lysosomal lipid storage diseases.
Cold Spring Harb Perspect. Biol. 3(6), 287-305.


Kumar S, Rezaei-Ghaleh N, Terwel D, Thal DR, Richard M, Hoch M, Mc Donald JM, Wüllner U, Glebov K, Heneka MT, Walsh DM, Zweckstetter M, Walter J. (2011)
Extracellular phosphorylation of the amyloid ß-peptide promotes formation of toxic aggregates during the pathogenesis of Alzheimer’s disease.
EMBO J. 30, 2255-65.


Tamboli IY, Hampel H, Tien NT, Tolksdorf K, Breiden B, Mathews PM, Saftig P, Sandhoff K, and Walter J. (2011)
Sphingolipid Storage Affects Autophagic Metabolism of the Ameloid Precursor Protein and Promotes Aß Generation.
J. Neuroscience, 31, 1849-1837.


Anitei M, Hoflack B. (2011)
Exit from the trans-Golgi network: from molecules to mechanisms.
Curr Opin Cell Biol. 23: 443-51.


Pocha SM, Wassmer T, Niehage C, Hoflack B, Knust E. (2011)
Retromer controls epithelial cell polarity by trafficking the apical determinant Crumbs.
Curr Biol. 21: 1111-7.


Zilly, F.E., Halemani, N.D., Walrafen, D., Spitta, L., Schreiber, A., Jahn, R. and Lang, T. (2011)
Ca2+ Induces Clustering of Membrane Proteins in the Plasma Membrane Via Electrostatic Interactions.
EMBO J. 30, 1209-1220.


Spandl, J., D. Lohmann, L. Kuerschner, C. Moessinger, and C. Thiele (2011)
Ancient Ubiquitous Protein 1 (AUP1) Localizes to Lipid Droplets and Binds the E2 Ubiquitin Conjugase G2 (Ube2g2) via Its G2 Binding Region.
J Biol Chem, 2011. 286(7): p. 5599-606.


Boson B, Granio O, Bartenschlager R, Cosset FL. (2011)
A concerted action of hepatitis C virus p7 and nonstructural protein 2 regulates core localization at the endoplasmic reticulum and virus assembly.
PLoS Pathog. 7(7):e1002144.


Long G, Hiet MS, Windisch MP, Lee JY, Lohmann V, Bartenschlager R. (2011)
Mouse hepatic cells support assembly of infectious hepatitis C virus particles.
Gastroenterology 141(3):1057-66.


Reiss S, Rebhan I, Backes P, Romero-Brey I, Erfle H, Matula P, Kaderali L, Poenisch M, Blankenburg H, Hiet MS, Longerich T, Diehl S, Ramirez F, Balla T, Rohr K, Kaul A, Bühler S, Pepperkok R, Lengauer T, Albrecht M, Eils R, Schirmacher P, Lohmann V, Bartenschlager R. (2011)
Recruitment and activation of a lipid kinase by hepatitis C virus NS5A is essential for integrity of the membranous replication compartment.
Cell Host Microbe 9(1):32-45.

Lorizate M, Kräusslich HG. (2011)
Role of lipids in virus replication.
Cold Spring Harb Perspect Biol.:a004820.


Baumgärtel, V., S. Ivanchenko, A. Dupont, M. Sergeev, P. Wiseman, H.-G. Kräusslich, C. Bräuchle, B. Müller, D.C. Lamb. (2011)
Dynamics of HIV budding site interactions with an ESCRT component visualized in live-cells.
Nature Cell Biol. 13:469-74.


Herzog, R., Schwudke, D., Schuhmann, K., Sampaio, J.L., Bornstein, S.R., Schroeder, M., and Shevchenko, A. (2011)
l informatics concept for high-throughput shotgun lipidomics based on the molecular fragmentation query language.

Genome Biol 12(1): R8.


Schuhmann, K., Herzog, R., Schwudke, D., Metelmann-Strupat, W., Bornstein, S.R., and Shevchenko, A. (2011).
Bottom-up shotgun lipidomics by higher energy collisional dissociation on LTQ Orbitrap mass spectrometers.
Anal Chem 83, 5480-5487.


Schwudke, D., Schuhmann, K., Herzog, R., Bornstein, S.R. and Shevchenko, A. (2011)
Shotgun lipidomics on high resolution mass spectrometers.
Cold Spring Harb Perspect Biol., 3(9), a004614.


Responsible: Editor
Latest Revision: 2014-03-21